Cortizone-10® Maximum Strength 1% Hydrocortisone


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Moisturizes skin with 10 nourishing ingredients while providing fast, long-lasting itch relief with maximum-strength hydrocortisone.

Moisturize and relieve itch with Cortizone-10® Maximum Strength 1% Hydrocortisone Itch Relief Ultra Soothing Cream. Get fast relief from itch associated with inflammation, eczema, psoriasis, rashes due to insect bites, poison ivy, poison oak, poison sumac, and minor skin irritations like rough, dry, red, chafed, and chapped skin. 

The maximum-strength hydrocortisone available over the counter helps relieve itch in less than 10 minutes and provide relief that lasts for hours. Maximum Strength Itch Relief Ultra Soothing Cream also includes 10 moisturizers for softer skin and aloe to soothe your skin.

Cortizone-10® is the #1 Doctor Recommended OTC Topical Anti-Itch Brand.*

  Relieves itch fast
  Long lasting
  Soothing aloe vera
  Fragrance free
  Dye free 
  Designed to be sting-free
  Formulated to be non-irritating
  Maximum-strength itch relief without a prescription

*2023 IQVIA Study

For itch associated with:


Insect bites

Poison Oak, Ivy, Sumac

Sizes: 1 oz tube, 2 oz tube

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Image of the Cortizone 10® Ultra Soothing Creme tube



  • Yes, both products are the same. The product’s name has changed from Cortizone-10® Maximum Strength Ultra Moisturizing Itch Relief Cream to Cortizone-10® Maximum Strength Ultra Soothing Itch Relief Cream and the packaging has been updated; however, no changes have been made to the formula.

  • No, there’s no safety seal on the tube. Do not use if the carton has been tampered with or if the product appears to have been used. We recommend keeping the product out of the reach of children.

  • Store in a cool, dry place out of direct sunlight.

  • No, for your own safety expired products should not be used.

  • Consult your healthcare professional before using if you are pregnant or breastfeeding and ask if Cortizone-10® can help.

  • Cortizone-10® can be applied externally to your skin. Please refer to the Drug Facts for indicated uses. For additional questions, consult your healthcare professional and ask if Cortizone-10® can help.

  • Use as directed. Apply to the affected area.

  • The product is fragrance free. So you’ll know it’s there, but nobody else will.

  • The “10” refers to 1.0% hydrocortisone in our products.

  • No, Cortizone-10® products are not tested on animals.

  • You may be able to use your HSA and FSA tax-preferred savings to purchase certain OTC products, including Cortizone-10®. The passage of the CARES Act by Congress includes provisions to restore OTC eligibility under tax-preferred HSAs and FSAs. Plan details vary, so save your receipt and check with your benefits or health provider for eligibility.